发明名称 IODINATED DERIVATIVES, PREPARATION AND USE THEREOF AS CONTRAST AGENTS IN X-RAY RADIOLOGY
摘要 <p>Polyiodinated derivatives of formula (I), wherein A is residue of an aromatic or aliphatic melecule; Za, Zb, Zc and Zd are Tz-Qz-Vz where Tz and Vz may be O, COND or NDCO, D may be H, alkyl or C1-6 hydroxyalkyl and Qz may be alkylene or hydroxyalkylene having 1 to 6 carbon atoms, or else Vz has the previous meaning or Qz and/or Tz are absent; Xa, Xb, Xc and Xd, which are the same or different, are (II), wherein Ar and Ar' are tri- or tetraiodinated phenyl groups with one or two optionally hydroxylated alkyl-substituted amide groups, and T, Q and V have one of the meanings of Tz, Qz or Vz, or X is (II'), wherein Ap and A'p have formula (II) above and T, Q and V have one of the meanings of Tz, Qz or Vz. Said materials are useful as contrast agents in X-ray radiology.</p>
申请公布号 WO1996009281(A1) 申请公布日期 1996.03.28
申请号 FR1995001213 申请日期 1995.09.20
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