发明名称 POLYIODO COMPOUNDS, THEIR PREPARATION AND THEIR USE IN X-RAY RADIOLOGY
摘要 Contrast agents for X-ray radiology having formula (I), wherein Ti, Vi, T'i, V'i, where i = 0, 1 or 2, are O, COND or NDCO where D is H, alkyl or hydroxyalkyl; Qi and Q'i, where i = 0, 1 or 2, are alkylene or hydroxyalkylene; Ari and Ar'i, where i = 1 or 2, are (II) or (III), wherein R, R3 and R4 are COOH, and R', R'3 and R'4 are CONR'1R'2 or N(R'1)COR'2 where R'1 and R'2 are H, C1-4 alkyl or hydroxyalkyl together comprising more than 4 OH, or R1 and R'i, where i = 0, 3 or 4, are CONR'1R'2 and N(R'1)COR'2, R'1 and R'2 together comprising at least 6 OH; or else are T-Q-V-Ar where T, Q and V may have the previous meanings and Ar has formula (II); and A is the residue of a molecule having a molar mass of less than 1200 and comprising two bonds capable of forming an amide or etheroxide group with T0 and T'0.
申请公布号 CA2200495(A1) 申请公布日期 1996.03.28
申请号 CA19952200495 申请日期 1995.09.20
申请人 GUERBET S.A. 发明人 LE LEM, GAEL;MEYER, DOMINIQUE
分类号 A61K49/04;C07C231/02;C07C237/46;(IPC1-7):C07C237/46 主分类号 A61K49/04
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