HIGH EFFICIENCY METHOD FOR ISOLATING TARGET SUBSTANCES USING A MULTISAMPLE SEPARATION DEVICE

摘要

Methods for separating target particles from a test medium in which the part icles are suspended. The method contemplates utilization of blocking or masking particles which block or mask unwanted biological deb ris which tends to interfere with formation of complexes by which the target particles can be isolated. After centrifugation, the mas king particles create a barrier between unwanted debris and test medium containing the target particles which permits the particles to be man ipulated or modified without removing them from the debr is. In a preferred aspect, magnetic separation techniques are used. In this aspe ct, non-magnetic 0.04 micron carboxylated polystyrene bl ocking particles are employed.