摘要 |
PCT No. PCT/IB95/00740 Sec. 371 Date May 12, 1997 Sec. 102(e) Date May 12, 1997 PCT Filed Sep. 6, 1995 PCT Pub. No. WO96/07753 PCT Pub. Date Mar. 14, 1996Method for synthesis of GalNAc alpha -serine or GalNAc alpha -threonine containing compounds, including at least one reaction where an alpha -saccharide or alpha -glycoside of GalNAca is used as gylcosyl donor and a derivative of serine of threonine is used as acceptor in a transglycosylation reaction with N-acetyl- alpha -D-galactosaminidase as the catalyst, wherein said acceptor has been modified in its N-terminal alpha -amino group and optionally in its c-terminal carboxyl group. |