发明名称 Ortho-substituted aromatic ether compounds and their use in pharmaceutical compositions for pain relief
摘要 PCT No. PCT/GB95/02030 Sec. 371 Date Feb. 21, 1997 Sec. 102(e) Date Feb. 21, 1997 PCT Filed Aug. 29, 1995 PCT Pub. No. WO96/06822 PCT Pub. Date Mar. 7, 1996The invention provides compounds of formula I: wherein A, B, D, X, R1, and R3 have any of the values defined in the specification, as well as N-oxides thereof, S-oxides thereof, pharmaceutically acceptable salts thereof, and in vivo hydrolizable esters and amides thereof, that are useful to relieve pain. The invention also provides pharmaceutical compositions as well as synthetic and therapeutic methods relating to such compounds.
申请公布号 AU3351995(A) 申请公布日期 1996.03.22
申请号 AU19950033519 申请日期 1995.08.29
申请人 ZENECA LIMITED 发明人 GLORIA ANNE BREAULT;JOHN OLDFIELD;HOWARD TUCKER;PETER WARNER
分类号 C07D213/79;C07C45/29;C07C45/41;C07C45/45;C07C45/51;C07C45/56;C07C45/68;C07C47/565;C07C47/575;C07C49/83;C07C65/21;C07C65/24;C07C65/26;C07C69/76;C07C69/94;C07C205/22;C07C205/37;C07C217/76;C07C217/86;C07C235/42;C07C235/44;C07C235/46;C07C235/60;C07C251/48;C07C255/37;C07C255/54;C07C259/10;C07C291/04;C07C311/21;C07C311/51;C07C317/18;C07C317/22;C07C323/20;C07D213/40;C07D213/80;C07D257/04;C07D277/56;C07D417/12;C07D521/00 主分类号 C07D213/79
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