发明名称 |
PREPARATION OF (8S)-8-FLUOROERYTHROMYCINS WITH N-F FLUORINATING AGENTS |
摘要 |
(8S)-8-fluoroerythromycins are prepared by reacting 8,9-anhydroerythromycin 6,9-hemiacetals or an N-oxide thereof with a carboxylic acid and an N-F fluorinating agent. The anhydro starting material may be prepared in situ from erythromycins or an N-oxide derivative thereof. The (8S)-8-fluoroerythromycin products are useful antibacterial agents.
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申请公布号 |
WO9608502(A1) |
申请公布日期 |
1996.03.21 |
申请号 |
WO1995US11098 |
申请日期 |
1995.09.05 |
申请人 |
ALLIEDSIGNAL INC. |
发明人 |
POSS, ANDREW, JOSEPH;SHIA, GEORGE, ANTHONY |
分类号 |
C07H17/08;(IPC1-7):C07H17/08 |
主分类号 |
C07H17/08 |
代理机构 |
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主权项 |
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地址 |
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