Weakly basic polymerizable monomers and polymers prepared therefrom

摘要

Weakly basic ethylenically unsaturated polymerizable monomers and polymers have been prepared. The monomers are represented by the structure (I):
<Chemistry id="chema01" num="0001"><Image id="ia01" he="23" wi="88" file="IMGA0001.TIF" imgContent="chem" imgFormat="TIFF" /></Chemistry>
wherein R is hydrogen or methyl, and R¹ is alkylene of 1 to 3 carbon atoms. The resulting polymers are water-soluble and cationic at acidic pH, but water-insoluble and neutral in charge at basic pH. The polymers are useful for precipitating nucleic acids.