摘要 |
A method of treating patients suffering from a respiratory disease using a programmable, hand-held, self-contained drug dispensing device (1) is disclosed. The drug dispensing device is comprised of a container (3) which includes a formulation (4) comprised of a respiratory drug enzyme and a suitable propellant which is generally in the form of a low boiling point propellant combined with an excipient which facilitates the suspension of the drug within the propellant. The drug dispensing device (1) is designed such that when a patient withdraws air from a mouthpiece (12) on the device (1), the patient's inspiratory flow is measured (15) and analyzed in terms of liters per minute as well as cumulative inspiratory volume in order to provide an inspiratory profile which can be used to to calculate an optimal point for the release (25, 26) of drug from the dispensing device (1). |