发明名称 Aminoalkanephosphinic acids and salts thereof
摘要 Compounds of formula I <IMAGE> (I) wherein R is diethoxymethyl, R1 is hydrogen, R2 is pyrid-3-ylmethyl and R3 is hydrogen, or R is cyclohexylmethyl, R1 is hydrogen and R2 is quinolin-4-ylmethyl, or R1 is hydroxy and R2 is 3,4-methylenedioxybenzyl, 1-(3,4-methylenedioxyphenyl)ethyl, and R3 is hydrogen, or R is benzyl, R1 is hydroxy, R2 is 1-(3,4-methylenedioxyphenyl)ethyl, and R3 is hydrogen, and salts thereof have GABAB-antagonistic properties and can be used for the treatment of diseases responsive to GABAB-antagonists.
申请公布号 US5500418(A) 申请公布日期 1996.03.19
申请号 US19940308040 申请日期 1994.09.16
申请人 CIBA-GEIGY CORPORATION 发明人 MICKEL, STUART J.
分类号 A61K31/66;A61P25/20;A61P25/24;A61P25/26;C07F9/30;C07F9/58;C07F9/60;C07F9/655;(IPC1-7):A61K31/665;C07D221/00 主分类号 A61K31/66
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