发明名称 |
Transdermal administration of oxybutynin |
摘要 |
The present invention is directed to the transdermal administration of oxybutynin together with a suitable permeation enhancer. The invention includes a transdermal drug delivery device comprising a matrix adapted to be placed in oxybutynin- and permeation enhancer-transmitting relation with the skin site. The matrix contains sufficient amounts of a permeation enhancer and of oxybutynin, in combination, to continuously administer to the skin for a predetermined period of time the oxybutynin to provide an effective therapeutic result. The invention is also directed to a method for the transdermal administration of a therapeutically effective amount of oxybutynin together with a skin permeation-enhancing amount of a suitable permeation enhancer.
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申请公布号 |
US5500222(A) |
申请公布日期 |
1996.03.19 |
申请号 |
US19950388767 |
申请日期 |
1995.02.15 |
申请人 |
ALZA CORPORATION |
发明人 |
LEE, EUN S.;NEDBERGE, DIANE E.;YUM, SU I. |
分类号 |
A61K9/00;A61K9/70;A61K31/135;A61K31/215;A61K31/216;A61K47/10;A61K47/14;A61K47/34;A61P13/02;A61P15/00;A61P25/00;(IPC1-7):A61F13/02 |
主分类号 |
A61K9/00 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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