发明名称 |
Radiolabelled platelet GPIIb/IIIa receptor antagonists as imaging agents for the diagnosis of thromboembolic disorders |
摘要 |
This invention provides novel radiopharmaceuticals that are radiolabeled cyclic compounds containing carbocyclic or heterocyclic ring systems which act as antagonists of the platelet glycoprotein IIb/IIIa complex; to the methods of using said radiopharmaceuticals as imaging agents for the diagnosis of arterial and venous thrombi; to novel reagents for the preparation of said radiopharmaceuticals; and to kits comprising said reagents. |
申请公布号 |
AU3452595(A) |
申请公布日期 |
1996.03.21 |
申请号 |
AU19950034525 |
申请日期 |
1995.10.30 |
申请人 |
THE DU PONT MERCK PHARMACEUTICAL COMPANY |
发明人 |
WILLIAM FRANK DEGRADO;SHAKER AHMED MOUSA;MICHAEL SWORIN;JOHN ANDREW BARRETT;DAVID SCOTT EDWARDS;THOMAS DAVID HARRIS;MILIND RAJOPADHYE;SHUANG LIU |
分类号 |
A61K38/12;A61K49/04;A61K51/00;A61K51/04;A61K51/08;C07B59/00;C07D213/82;C07D257/00;C07D259/00;C07D277/60;C07D401/00;C07D401/12;C07D401/14;C07D413/12;C07K5/10;C07K5/103;C07K7/64;C07K14/75;C07K17/02 |
主分类号 |
A61K38/12 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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