DECOMPOSITION DETECTING METHOD OF OLIGONUCLEOTIDE LABELED WITH LUMINOUS LABEL

摘要

Method for controlling the light emission of a single-stranded oligonucleotide covalently labelled with a light-emitting label comprises adding a DNA-binding cpd. to a soln. of the labelled oligonucleotide, where the DNA-binding cpd. is capable of interacting with the label to modify its light emission. Also claimed are: (1) a method for detecting cleavage of a labelled oligonucleotide and (2) a method for detecting a target nucleic acid sequence in a sample, comprising measuring the light emission of a PCR mixt.