| 摘要 |
PURPOSE: To obtain an anticancer agent, containing a calponin gene as an active ingredient and effective in treating and preventing cancer especially suppression of cancer metastatic ability due to its ability to reduce both the tumorigenicity and the metastasis of a cancerous cell. CONSTITUTION: This anticancer agent contains a calponin gene (preferably a human-derived calponin gene containing a base sequence of the formula) as an active ingredient. the calponin gene is preferably sealed in a content of 10-50wt.% in a lipsome using N-[1-(2,3-dioleyloxy)-propyl]-N,N,N- trimethylammonium methyl sulfate as a raw material for use from the viewpoint of cytotoxicity. The daily does of the anticancer agent for an adult is preferably 20-600mg expressed in terms of the weight of the calponin. A recombinant vector containing the calponin gene may be used as the calponin gene. |
