摘要 |
<p>PCT No. PCT/CH92/00049 Sec. 371 Date Nov. 13, 1992 Sec. 102(e) Date Nov. 13, 1992 PCT Filed Mar. 11, 1992 PCT Pub. No. WO92/16536 PCT Pub. Date Oct. 1, 1992.Novel, racemic and optically active phosphorus compounds of the formula <IMAGE> I wherein R signifies lower alkyl, lower alkoxy or a protected hydroxy group, R1 signifies a five membered heteroaromatic ring, R2 stands for lower alkyl or lower alkoxy and n represents the number 0, 1 or 2, are described. The compounds of formula I serve in the form of complexes with a metal of Group VIII as catalyst for asymmetric hydrogenations and for enantioselective hydrogen displacements in prochiral allylic systems.</p> |
申请人 |
F. HOFFMANN-LA ROCHE & CO. AKTIENGESELLSCHAFT |
发明人 |
BROGER, EMIL, ALBIN;FORICHER, JOSEPH;HEISER, BERND;SCHMID, RUDOLF |