发明名称 |
Cyclic cs-1 peptidomimetics, compositions and methods of using the same |
摘要 |
The present invention contemplates a cyclic peptide that inhibits the binding between the VLA-4 receptor expressed on inflammatory leukocytes and the fibronectin CS-1 peptide expressed on endothelial cells that are involved in immunoinflammatory disease states. Pharmaceutical compositions containing a contemplated cyclic peptide and processes for treating immunoinflammatory conditions using a binding-inhibitory cyclic peptide are also disclosed. |
申请公布号 |
AU3495395(A) |
申请公布日期 |
1996.03.14 |
申请号 |
AU19950034953 |
申请日期 |
1995.08.25 |
申请人 |
CYTEL CORPORATION |
发明人 |
THOMAS S ARRHENIUS;MARIANO J ELICES;ANNA TEMPCZYK;ZHONGLI ZHENG |
分类号 |
A61K38/00;C07K5/083;C07K5/103;C07K5/117;C07K5/12;C07K14/78 |
主分类号 |
A61K38/00 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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