Composite dna-binding proteins and materials and methods relating thereto

摘要

This invention provides novel chimeric proteins and DNA sequences encoding them which are useful for regulated transcription of target genes in genetically engineered cells or organisms containing them. Target gene constructs and other materials useful for practicing the invention are also disclosed. Target gene constructs include a recombinant DNA sequence which is capable of binding to at least two heterologous DNA binding domains, e.g. in the form of a composite DNA binding protein or protein complex.