发明名称 |
NEW IODIZED BORON COMPOUNDS USEFUL AS X RAY CONTRASTING AGENTS, AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM |
摘要 |
<p>The invention relates to new organic boron compounds having a monomer structure (I): ÄBxCyH(x+y-t-w)ItZwÜ, 2/rQ and a dimer structure (II): äÄB12H(12-t-w)ItZwÜ-N(R)-ÄB12H(12-t-w)ItZwÜü, 4/rQ, caracterized in that they contain a high molar percentage of iodine, and are useful as radio-opaque agents in uroangiography, cardioangiography, etc., as well as for selectively visualizing organs or body systems such as the liver, the spleen or the lymphatic system. The compounds having the general formulas (I) and (II) are also useful in the selective therapy of tumors. The invention also relates to pharmaceutical preparations which contain the claimed compounds having the general formulas (I) and (II).</p> |
申请公布号 |
EP0700918(A1) |
申请公布日期 |
1996.03.13 |
申请号 |
EP19950913175 |
申请日期 |
1995.03.23 |
申请人 |
CENTRO INVESTIGACION JUSTESA IMAGEN S.A. |
发明人 |
MARTIN JIMENEZ, JOSE, L.;SPECK, ULRICH;CARRETERO COLON, JOSE, MARIA;MARTINEZ SANZ, ANTONIO;BOHLE, FLORIAN;KRAUSE, WERNER |
分类号 |
A61K41/00;A61K49/04;C07F5/02;(IPC1-7):C07F5/02 |
主分类号 |
A61K41/00 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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