发明名称 |
Nitroglycerine plaster and process for its production |
摘要 |
PCT No. PCT/EP92/01169 Sec. 371 Date Mar. 14, 1994 Sec. 102(e) Date Mar. 14, 1994 PCT Filed May 25, 1992 PCT Pub. No. WO92/22292 PCT Pub. Date Dec. 23, 1992.The invention relates to a dermal plaster for the transdermal provision of nitroglycerin comprising a carrier film and a removable protective film and an adhesive mass containing nitroglycerine on the basis of a cross-linked acrylate-vinyl acetate copolymer in which the monomer mix used for polymerization consists essentially of 21 to 40% wt. vinyl acetate, 55 to 70% wt. of an acrylic acid C2-8 alkyl ester and 3 to 10% wt. of an acrylic acid C2-4 hydroxyalkyl ester and which is cross-linked by heating and the removal of any solvents present after the addition of a cross-linking agent and the nitroglycerin.
|
申请公布号 |
US5498418(A) |
申请公布日期 |
1996.03.12 |
申请号 |
US19940142316 |
申请日期 |
1994.03.14 |
申请人 |
SCHWARZ PHARMA AG;LTS LOHMANN THERAPIE-SYSTEMME GMBH & CO. KG |
发明人 |
BEUTNER, DIETER;VON KNOBELSDORFF, HENNING;WOLFF, HANS-MICHAEL;HOFFMANN, RAINER;MECONI, REINHOLD;KLEIN, ROBERT P. |
分类号 |
A61K9/70;A61K31/21;A61P9/08;A61P9/10;(IPC1-7):A61F13/00 |
主分类号 |
A61K9/70 |
代理机构 |
|
代理人 |
|
主权项 |
|
地址 |
|