发明名称 Naphthamide derivatives
摘要 The new naphthamide derivatives according to the invention are characterized in that they correspond to the general formula (I), <IMAGE> (I) where X: represents either a hydrogen atom, or a chlorine or bromine atom, or an amino or aminoalkyl group, an aminosulphamoyl group, a sulphur-containing group such as thiocyanate, alkylthio, alkylsulphinyl or alkylsulphonyl, or a methoxy group, or a nitro group, or a cyano group, or an electron-attracting group; Y: represents an alkyl or alkenyl residue; Z: represents the residues originating from 2-aminomethyl-N-alkylpyrrolidine, 2-aminoethyl-N,N-diethylamine, 2-(aminoethyl)morpholine, 2-aminoethyl-N,N-dibutylamine, 4-amino-N-butylpiperidine or 2-(aminoethyl)pyrrolidine; R: a hydrogen or an OCH3 substituent. These new derivatives may be employed in the preparation of medicinal products intended for use as an antipsychotic, psychostimulatory, anti-autistic or antidepressant agent, an agent for treating Parkinson's disease or an antihypertensive agent.
申请公布号 US5498628(A) 申请公布日期 1996.03.12
申请号 US19920965927 申请日期 1992.10.23
申请人 INSTITUT NATIONAL DE LA SANTE ET DE LA RECHERCHE MEDICALE 发明人 ROGNAN, DIDIER;MANN, ANDRE;WERMUTH, CAMILLE-GEORGES;MARTRES, MARIE-PASCALE;GIROS, BRUNO;SOKOLOFF, PIERRE;SCHWARTZ, JEAN-CHARLES;LECOMTE, JEANNE-MARIE;GARRIDO, FABRICE
分类号 A61K31/165;A61K31/18;A61K31/26;A61K31/275;A61K31/40;A61K31/445;A61K31/4468;A61K31/535;A61K31/5375;A61P9/12;A61P25/00;A61P25/18;A61P25/26;C07C235/66;C07C255/55;C07D207/09;C07D211/58;C07D265/30;C07D295/13;(IPC1-7):A61K31/40 主分类号 A61K31/165
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