摘要 |
A method for introducing a functionalising group as a ring substituent into a nitrogen-containing heterocyclic aromatic compound which method comprises reacting a compound containing the functionalising group with the heterocyclic aromatic compound in the presence of elemental fluorine. The functionalising group may be a group -ROH or a group -Sra or a group -NRbRc wherein R, Ra, Rb and Rc are each independently selected from the following groups which may be optionally substituted: alkyl, allyl, alkoxy, acyl, acyloxy, cycloalkyl and aryl. |