BIOLOGICALLY ACTIVE FRAGMENTS OF GLUCAGON-LIKE INSULINOTROPIC PEPTIDE
摘要
N-terminal truncated forms of glucagon-like insulinotropic peptide (GLP-1) and analogs thereof are provided. The claimed polypeptides promote glucose uptake by cells but do no stimulate insulin expression or secretion. The invention also provides methods for treating diabetes and pharmaceutical formulations comprising the claimed polypeptides.
申请公布号
WO9606628(A1)
申请公布日期
1996.03.07
申请号
WO1995US10793
申请日期
1995.08.25
申请人
ELI LILLY AND COMPANY;JOHNSON, WILLIAM, TERRY;YAKUBU-MADUS, FATIMA, EMITSELA