发明名称 |
MARKER FOR INDIVIDUALS SUSCEPTIBLE TO ALCOHOLISM |
摘要 |
The present invention relates to methods for diagnosis of susceptibility to alcoholism or the pathological effects of alcoholism based on detection of a genetic marker in an individual. The present invention is directed generally to methods and associated compositions and kits for detecting the presence of arylsulfatase A (ASA) pseudodeficiency (PD) mutations in humans. Detection of these mutations has been surprisingly found to be a strong indicator for susceptibility to alcoholism and/or susceptibility to alcohol's pathological effects, as well as an important marker in evaluating the likelihood of metachromatic leukodystrophy (MLD).
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申请公布号 |
CA2198863(A1) |
申请公布日期 |
1996.03.07 |
申请号 |
CA19952198863 |
申请日期 |
1995.08.31 |
申请人 |
ALGENE LLC |
发明人 |
MANOWITZ, PAUL;PORETZ, RONALD D.;PARK, DAVID;RICKETTS, MICHAEL |
分类号 |
C07H21/04;C07K16/40;C12Q1/68;G01N33/573;G01N33/68;(IPC1-7):C12Q1/68 |
主分类号 |
C07H21/04 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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