| 摘要 |
<p>PCT No. PCT/FR95/00727 Sec. 371 Date May 27, 1997 Sec. 102(e) Date May 27, 1997 PCT Filed Jun. 6, 1995 PCT Pub. No. WO96/05294 PCT Pub. Date Feb. 22, 1996Method for preparing purified influenza antigens from a fluid containing influenza virus, comprising the steps of concentration, purification, fragmentation and, where appropriate, inactivation, characterized in that: A. either the purification step entails several ultracentrifugation steps separated by a filtration step, B. or the fragmentation step is performed on the live virus in the presence of an amphiphilic nonionic detergent, followed by a removal of undesirable substances by filtration, retaining all of the viral constituents, or these two steps are carried out in any order.</p> |
