Heterocyclic compounds having angiotensin II antagonistic activity and use thereof

摘要

This invention relates to a compound represented by the formula <IMAGE> (I) wherein the ring A stands for a 5-10 membered aromatic heterocyclic group optionally having, besides R1 and R2, further substituents; R1 stands for an optionally substituted hydrocarbon residue which is optionally bonded through a hetero-atom; R2 stands for a group capable of liberating proton in a living body or a group convertible thereinto; R3 stands for an 5-7 membered optionally substituted heterocyclic residue having, as a group capable of constituting the ring, carbonyl group, thiocarbonyl group, an optionally oxidized sulfur atom or a group convertible into them; X shows that the ring Y and the ring W are bonded to each other directly or through a spacer having an atomic length of two or less; the ring W and the ring Y are each an optionally substituted aromatic hydrocarbon or aromatic heterocyclic residue; and n denotes an integer of 1 to 3, or a salt thereof and to an angiotensin II antagonistic agent containing the compound (I) or a salt thereof.