发明名称 Antibodies and their use
摘要 The invention relates to antibodies which is capable of binding the monocyte chemoattractant protein 1 (MCP-1) receptor CCR2, especially those which are capable of acting either as an antagonist or agonist. The claimed antobodies can be used for in vitro and/or in vivo diagnostic, for screening and detection of tissues and classes of cells expressing the MCP-1 receptor, for screening for new drugs and for therapeutic use. The invention also relates to a preparation comprising the claimed antibody and a micro-organism or cell-line capable of producing the claimed antibody.
申请公布号 SE9600820(D0) 申请公布日期 1996.03.01
申请号 SE19960000820 申请日期 1996.03.01
申请人 PHARMACIA AB 发明人 JOSE MARIO MELLADO *GARCIA;JOSE MIGUEL RODRIGUEZ *FRADE;CARLOS MARTINEZ *ALONSO;PETER *LIND
分类号 C12N15/02;A61K31/00;A61K38/00;A61K39/395;A61K49/00;A61P9/00;A61P9/10;A61P11/00;A61P17/00;A61P17/06;A61P19/00;A61P19/02;A61P25/28;A61P29/00;A61P35/00;A61P37/00;A61P37/02;C07K16/28;C12N5/10;C12P21/08;G01N33/15;G01N33/53;G01N33/566;G01N33/569;G01N33/68;(IPC1-7):A61K/ 主分类号 C12N15/02
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