New malonic acid derivs. of sugars or linear poly:ol

摘要

Malonic acid derivs. of formula (I) are new. R1-R3 = H, (CH2)mX or CH2O(CH2)mX1, or R1+R2 = 6-membered carbocycle or heterocycle substd. by at least one of R4, R5 and R6; A, B = O, S, NH, NHCO, OCNH, OCO, COO, NHCOO, OCONH, SCO, OCS, OCS2, S.CSO, NHCS2, SCS.NH or CH2; Z = pyranose, furanose, open-chained polyol, or -YX6; Y = O(CX2X3)n, (CX2X3)n, (CX2R7)n, (CR7R8)n, CH2(CX2X3)n, or a satd. or unsatd. 6-membered carbocycle or heterocycle with at least one substit. R9, or a combination of a ring and O(CX2X3)n, (CX2X3)n, (CX2R7)n or (CR7R8)n; R4-R6 = H, OH, (CH2)qX4, CH2O(CH2)qX5 or NH.COMe; R7-R9 = H, OH, (CH2)qX4 or CH2O(CH2)qX5; X, X1-X5 = H, NH2, COOH, OH, CH2OH, CH2NH2, 1-20C alkyl or 6-10C aryl; X6 = OH or -CR3(COOH)2; m, n, q = 1-20.