发明名称 N,N-DISUBSTITUTED AMIC ACID DERIVATIVE
摘要 <p>A compound represented by general formula (I), a medicinally acceptable salt or ester thereof, and an antineoplastic containing the same as the active ingredient, wherein Ar?1, Ar2, Ar3 and Ar4¿ represent each aryl or heteroaryl, A represents an optionally substituted hydrocarbon group; X and Y represent each oxygen, sulfur, carbonyl, -CHRa- (Ra being hydrogen or lower alkyl) or -NRb- (Rb being hydrogen or lower alkyl), or X and Y are combined together to represent vinylene or ethynylene; R?1, R2, R3, R8 and R9¿ represent each hydrogen, halogeno, hydroxy, lower alkyl or lower alkoxy; R?4 and R5¿ represent each hydrogen, halogeno, hydroxy, amino, nitro, cyano, carboxy, lower alkoxycarbonyl, carbamoyl, lower alkylcarbamoyl, lower alkyl, lower hydroxyalkyl, lower fluoroalkyl or lower alkoxy; R6 represents lower alkyl; and R7 represents hydrogen or lower alkyl; provided when one of X and Y represents oxygen, sulfur or -NRb-, the other of them represents carbonyl or -CHRa-.</p>
申请公布号 WO1996005169(P1) 申请公布日期 1996.02.22
申请号 JP1995001589 申请日期 1995.08.10
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