| 摘要 |
A fused pyridazine compound represented by general formula (I) and having the inhibitory effect against cyclic GMP-phosphodiesterase (cGMP-PDE), and a pharmacologically acceptable salt thereof. These compounds are useful as preventives and remedies for diseases against which the cGMP-PDE inhibitory effect is efficacious, such as ischemic heart diseases including angina pectoris, myocardial infarct, and chronic and acute cardiac failures, pulmonary hypertension, arteriosclerosis, and bronchial asthma.
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| 申请人 |
EISAI CO., LTD.;WATANABE, NOBUHISA;KABASAWA, YASUHIRO;TAKASE, YASUTAKA;OZAKI, FUMIHIRO;ISHIBASHI, KEIJI;MIYAZAKI, KAZUKI;MATSUKURA, MASAYUKI;SOUDA, SHIGERU;MIYAKE, KAZUTOSHI;ISHIHARA, HIROKI;KODAMA, KOHTARO;ADACHI, HIDEYUKI |
发明人 |
WATANABE, NOBUHISA;KABASAWA, YASUHIRO;TAKASE, YASUTAKA;OZAKI, FUMIHIRO;ISHIBASHI, KEIJI;MIYAZAKI, KAZUKI;MATSUKURA, MASAYUKI;SOUDA, SHIGERU;MIYAKE, KAZUTOSHI;ISHIHARA, HIROKI;KODAMA, KOHTARO;ADACHI, HIDEYUKI |
