发明名称 Bimodal molecular weight hyaluronate formulations and methods for using same
摘要 Compositions and methods useful for protecting human or animal eye cell layers and tissues exposed to trauma, e.g., during surgery, are disclosed. In one embodiment, the method comprises administering a protective amount of an ophthalmically acceptable aqueous composition containing a first alkali metal and/or alkaline earth metal hyaluronate fraction having a molecular weight of at least about 2 million, for example, in the range of about 2 million to about 4 million, and a second alkali metal and/or alkaline earth metal hyaluronate fraction having a molecular weight of about 200,000 to about 800,000, for example, in the range of about 300,000 to 700,000, to eye cell layers and tissues prior to the exposure to the trauma.
申请公布号 US5492936(A) 申请公布日期 1996.02.20
申请号 US19920965581 申请日期 1992.10.23
申请人 ALLERGAN, INC. 发明人 FRANCESE, JAMES E.;CHRIST, F. RICHARD
分类号 A61K9/00;A61K31/715;A61K31/728;(IPC1-7):A61K47/00 主分类号 A61K9/00
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