Recovery of insoluble biosynthetic products

摘要

There is disclosed a process for the recovery of an insoluble fermentation product from a solid phase cell mass, the process comprising treating the fermentation broth to solubilize the cell mass and separating by known methods the liquid phase from the insoluble (product-containing) phase. The solubilization of the cell mass may be carried out by one or mere treatments with an alkali or acid compound or by enzymatic treatment of the cell mass to lyze the cells.