发明名称 Condensed heterocyclic compounds useful for inhibiting acyl-CoA
摘要 Novel compound represented by the formula: <IMAGE> wherein ring A, ring B and ring C each stands for an optionally substituted benzene ring; X stands for -NR- wherein R stands for hydrogen atom or an optionally substituted hydrocarbon group, -O- or -S-; Y stands for -(CH2)n- wherein n denotes 1 or 2 or -NH-; and Ra stands for a hydrogen atom or an optionally substituted hydrocarbon group, provided that when ring C is unsubstituted or substituted only at para-position, ring B is substituted at least at ortho-position or a salt thereof which have an excellent acyl-CoA: cholesterol acyltransferase inhibiting action and cholesterol-lowering activity, their production and medicinal use.
申请公布号 US5492929(A) 申请公布日期 1996.02.20
申请号 US19930165925 申请日期 1993.12.14
申请人 TAKEDA CHEMICAL INDUSTRIES, LTD. 发明人 NATSUGARI, HIDEAKI;SUGIYAMA, YASUO;IKEURA, YOSHINORI
分类号 C07D209/14;C07D209/18;C07D209/40;C07D307/79;C07D307/81;C07D307/82;C07D333/58;C07D333/60;C07D333/66;(IPC1-7):A61K31/34 主分类号 C07D209/14
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