Certain pyridyl-benzopyran derivatives

摘要

The present invention relates to novel benzopyran derivatives of formula (I) which have exellent effectiveness in the treatment of asthma as well as hypertension. <IMAGE> (I) wherein: R1 is -CN, -NO2, -OCX1X2X3, -NH2, -NHSO2RA, <IMAGE> -SO2RC or -SO2NRCRD wherein X1, X2 and X3 are, each independently, F, Cl or H, except for that X1, X2 and X3 may not be hydrogen atom simulaneously; RA and RB are, each independently, a hydrogen atom, or a C1-6 alkyl group or an optionally substituted phenyl group with a halogen atom, or a straight or branched C1-3 alkyl group; and RC and RD are, each independently, a hydrogen atom or a C1-6 alkyl group or an optionally substituted phenyl group with a halogen atom, or a straight or branched C1-3 alkyl group; R2 is a C1-4 straight or branched alkyl group; R3 is a C1-4 straight or branched alkyl group, <IMAGE> wherein RG and RH are, each independently, a C1-6 alkyl group or optionally substituted phenyl group with a halogen atom, or a straight or branched C1-3 alkyl group, A and B are, each independently, S or O; X is N or N->O; Y is a hydrogen or halogen atom, or an amino, hydroxy, a lower alkoxy or lower alkyl group.