ADHESION PROTEIN MICELLES

摘要

A micelle of an adhesion protein which naturally includes a phosphatidylinositol lipid anchor, the micelle being capable of binding multivalently to a plurality of target molecules on a cell surface. The micelle can be used to ameliorate diseases in which binding of T-cells to other cells is a continuing factor, e.g. in autoimmune diseases like rheumatoid arthritis, allograft rejection and graft-versus-host diseases.