PHENYLACETAMIDES HAVING LEUKOTRIENE-ANTAGONISTIC ACTION

摘要

Phenylacetamides of formula (I) wherein the substituent containing a -CONR<3>- is bound to the 3- or 4- position of the phenol system; the substituent containing B is bound to the benzene ring at any free position; R<1> is hydrogen, fluorine, chlorine or -OCH3; R<2> is hydrogen, fluorine, chlorine or bromine; R<3> is hydrogen or methyl; B is a 5-tetrazolyl group or -COOR<4>, wherein R<4> is hydrogen, a (C1-C4)-alkyl or a phenylalkyl group of less than 10 carbon atoms; m and n are integers from 0 to 6, with the proviso that m + n is less or equal to 6; have leukotriene antagonistic action.