| 发明名称 |
TERPENE-QUINONE WITH ANTITUMOR ACTIVITY |
| 摘要 |
Terpene-quinone with antitumor activity defined from a cyclocondensation reaction of Diels-Alder, used to obtain families or series of said compounds having a new structure and presenting a cytotoxic activity to cellular cultures P-388, A-549, HT-29 and MEL-28, with levels of IC50 lower than 1 microgram per unit of millilitre.
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| 申请公布号 |
CA2173157(A1) |
申请公布日期 |
1996.02.15 |
| 申请号 |
CA19952173157 |
申请日期 |
1995.08.01 |
| 申请人 |
PHARMA MAR, S.A. |
发明人 |
GARCIA GRAVALOS, MARIA DOLORES;GORDALIZA ESCOBAR, MARINA;MIGUEL DEL CORRAL SANTANA, JOSE MARIA;MAHIQUES BUJANDA, MARIA DEL MAR;SAN FELICIANO MARTIN, ARTURO |
| 分类号 |
C07D303/12;A61K31/12;A61K31/122;A61K31/215;A61K31/335;A61K31/336;A61P35/00;C07C39/14;C07C39/225;C07C45/69;C07C46/00;C07C49/653;C07C50/10;C07C50/14;C07C50/32;C07C61/35;C07C69/017;C07C69/157;C07C69/753;C07C69/757;C07C225/30;C07D303/16;(IPC1-7):C07C50/14;C07C43/188;C07C217/94 |
主分类号 |
C07D303/12 |
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