NOVEL AMINE DERIVATIVE, PROCESS FOR PRODUCING THE SAME, AND USE THEREOF AS ANTIARRHYTHMIC

摘要

A novel amine derivative represented by general formula (I) and a salt thereof, each being useful as an antiarrhythmic, wherein, for example, A represents -(CH2)-O-, -(CH2)2-O- or -(CH2)2-NH-; B represents -(CH2)2-; R1 represents hydrogen, halogen, nitro, 1-pyrrolyl, acetamido, amino or dimethylamino; R2 represents hydrogen or nitro; R3 and R4 represent each hydrogen; R8a and R8b both represent chloro or methoxy at the same time; R9 represents hydrogen or amino; R represents methyl; and X represents methanesulfonamido, 1-imidazolyl or nitro.