Novel pyrrolinone-based compounds mimic or inhibit the biological and/or chemical activity of peptides, including peptide .beta.-strand conformations. Certain compounds contain functionalized pyrrolinone units in place of one or more amino acids of a target peptide.
申请公布号
CA2196608(A1)
申请公布日期
1996.02.15
申请号
CA19952196608
申请日期
1995.08.02
申请人
TRUSTEES OF THE UNIVERSITY OF PENNSYLVANIA (THE)
发明人
HIRSCHMANN, RALPH F.;SMITH, AMOS B., III;SPRENGELER, PAUL;HOLCOMB, RYAN C.;KEENAN, TERENCE;WOOD, JOHN L.;GUZMAN, MARK;PASTERNAK, ALEXANDER
