发明名称 |
REMEDY FOR CORNEAL DISEASES |
摘要 |
A remedy for corneal diseases containing at least one member selected from among hexapeptides represented by the following general formula (I): A-B-Pro-C-D-E and pharmaceutically acceptable salts thereof and a pharmaceutically acceptable carrier. In said formula (I) A represents arginine or lysine with the terminal amino group thereof removed, alkylated or acylated; B represents arginine, lysine or histidine; Pro represents proline; C represents tyrosine, tryptophan or phenylalanine; D represents valine, isoleucine or leucine; and E represents valine, isoleucine or leucine with the terminal carboxyl group thereof substituted by -COOR, -CH2OR or CONHR, wherein R represents hydrogen or C1-C4 alkyl.
|
申请公布号 |
WO9604002(A1) |
申请公布日期 |
1996.02.15 |
申请号 |
WO1995JP01549 |
申请日期 |
1995.08.04 |
申请人 |
TSUMURA & CO.;OKAMOTO, SINSEIRO;AMAGAYA, SAKAE;SAKAMOTO, KENJI;KANITANI, MASANAO |
发明人 |
OKAMOTO, SINSEIRO;AMAGAYA, SAKAE;SAKAMOTO, KENJI;KANITANI, MASANAO |
分类号 |
A61F9/007;A61K38/00;C07K5/11;C07K7/02;C07K7/06;C07K14/485;C07K14/52;(IPC1-7):A61K38/07;A61K38/08;A61K38/18;A61K38/39 |
主分类号 |
A61F9/007 |
代理机构 |
|
代理人 |
|
主权项 |
|
地址 |
|