摘要 |
PCT No. PCT/US92/06132 Sec. 371 Date May 16, 1994 Sec. 102(e) Date May 16, 1994 PCT Filed Jul. 23, 1992 PCT Pub. No. WO93/01806 PCT Pub. Date Feb. 4, 1993.An artificial blood substitute comprising Lewis acid-Lewis base salt film microcapsule having a perfluorocarbons encapsulated therein. The Lewis base may be a polyoxyalkylene adduct of an amine, having the structure: <IMAGE> in which, independently, <IMAGE> R2 = CH2OR1 or CH2N(R1)2 <IMAGE> and R4 = H, CH3 or alkyl, and said Lewis acid may be a polyoxyalkylene derivative of a polymeric acid having the structure <IMAGE> in which c- and d- type repeat units are randomly distributed within the polymer, c=70 to 3150, c-type repeat units comprise from 50-90% of the total polymer.
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