发明名称 |
Novel elastase inhibitors |
摘要 |
This invention relates to compounds which are inhibitors of elastase, particularly human neutrophil elastase. The inhibitors are short, synthetic peptides in which the P2 moiety is substituted with various nitrogen-containing heterocyclic groups. As inhibitors of human neutrophil elastase, the compounds are useful in the treatment of a patient afflicted with a neutrophil associated inflammatory disease. |
申请公布号 |
ZA9504430(B) |
申请公布日期 |
1996.02.13 |
申请号 |
ZA19950004430 |
申请日期 |
1995.05.30 |
申请人 |
MARION MERRELL DOW INC. |
发明人 |
WILLIAM ARTHUR METZ JR;STEVEN LEE GALLION;JOSEPH PAUL BURKHART;MICHAEL RICHARD ANGELASTRO;NORTON PAUL PEET |
分类号 |
A61K38/55;A61K38/00;A61P1/00;A61P7/02;A61P11/00;A61P19/06;A61P21/00;A61P29/00;C07K5/06;C07K5/08;C07K5/083;C07K5/09;C07K5/10;C07K5/103;C12N9/99 |
主分类号 |
A61K38/55 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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