发明名称 N-acyl sulfamic acid esters (or thioesters), N-acyl sulfonamides, and N-sulfonyl carbamic acid esters (or thioesters) as hypercholesterolemic agents
摘要 The present invention is directed to compounds useful for the regulation of cholesterol of Formula I, methods for using them and pharmaceutical compositions thereof, <IMAGE> I wherein X and Y are oxygen, sulfur, or (CR'R'')n wherein n is 1 to 4; R is hydrogen, alkyl, or benzyl; R1 and R2 are phenyl, substituted phenyl, naphthyl, substituted naphthyl, an aralkyl group, an alkyl chain, adamantyl, or a cycloalkyl group.
申请公布号 US5491172(A) 申请公布日期 1996.02.13
申请号 US19940223932 申请日期 1994.04.13
申请人 WARNER-LAMBERT COMPANY 发明人 LEE, HELEN T.;PICARD, JOSEPH A.;SLISKOVIC, DRAGO R.;WIERENGA, WENDELL
分类号 A61K31/18;C07C307/02;C07C311/51;C07D311/84;(IPC1-7):A61K31/18 主分类号 A61K31/18
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