Preparat for anvendelse in vitro, udödelig, transformert cellelinje og humant, monoklonalt antistoff, samt sett eller utstyr for anvendelse ved påvisning in vitro av tilstedeværelse av Pseudomonas aeruginosa

摘要

Cell lines have been produced that secrete human monclonal antibodies capable of binding to the lipopolysaccharide molecules of selected Pseudomonas aeruginosa IATS serotypes. Pharmaceutical compositions containing these antibodies, which can be in combination with other monoclonal antibodies, blood plasma fractions and antimicrobial agents, and the prophylactic and therapeutic use of such compositions in the management of infections are included. Prior to filing of this patent application the continuous transformed human cell lines 1C1, 6D6, and 8H7 described herein were deposited in the American Type Culture Collection and given the designations CRL 8941, 9171, and. 9258, respectively.