发明名称 |
Use of swinholide a for severing and depolymerizing actin |
摘要 |
The present invention provides a method of severing and depolymerizing filamentous actin involving the use of the marine product Swinholide A. This invention also provides methods of treating mammals afflicted with conditions or diseases involving pathological extra cellular actin, in particular with respiratory conditions or diseases where filamentous actin contributes to pathologically high viscosities of the mucous or sputum in the lungs of those mammals. |
申请公布号 |
AU2967095(A) |
申请公布日期 |
1996.02.09 |
申请号 |
AU19950029670 |
申请日期 |
1995.07.10 |
申请人 |
THE GOVERNMENT OF THE UNITED STATES OF AMERICA AS REPRESENTED B;RESEARCH FOUNDATION OF THE STATE UNIVERSITY OF NEW YORK |
发明人 |
MICHAEL R BUBB;EDWARD D KORN;ILAN SPECTOR |
分类号 |
A61K31/365 |
主分类号 |
A61K31/365 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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