| 发明名称 |
INDENE SPLA2 INHIBITORS |
| 摘要 |
A class of novel indene-1-functional compounds is disclosed together with the use of such indene compounds for inhibiting sPLA2 mediated release of fatty acids for treatment of conditions such as septic shock. The compounds are indene-1-acetamides, indene-1-acetic acid hydrazides, and indene-1-glyoxylamides.
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| 申请公布号 |
CA2195432(A1) |
申请公布日期 |
1996.02.08 |
| 申请号 |
CA19952195432 |
申请日期 |
1995.07.20 |
| 申请人 |
ELI LILLY AND COMPANY;SHIONOGI & CO., LTD. |
发明人 |
DILLARD, ROBERT DELANE;HAGISHITA, SANJI;OHTANI, MITSUAKI |
| 分类号 |
A61K31/165;A61K31/195;A61P9/00;A61P11/00;A61P27/16;A61P29/00;A61P31/04;A61P37/08;A61P43/00;C07C45/46;C07C45/65;C07C49/755;C07C59/64;C07C59/66;C07C59/72;C07C69/734;C07C235/32;C07C235/34;C07C235/78;C07C243/32;C07C309/59;C07C323/61;C07C327/44;C07F9/09;C07F9/38;C07F9/40;(IPC1-7):C07C235/78;A61K31/19;C07D333/24;A61K31/33;C07D207/337;C07C327/40;C07C323/41;C07C309/51;C07D307/54;A61K31/66 |
主分类号 |
A61K31/165 |
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