CHELATOR IDAC-2 AND METHOD FOR PURIFYING CHELATOR CONJUGATED COMPOUNDS

摘要

A method for removing unbound labeling reagent from a compositioncomprising bound and unbound labeling reagents in which a chelator-matrix conjugate capable of binding unbound labeling reagent is contacted with a biomolecule labeling reaction mixture, by which the unbound labeling reagent is scavenged by the chelator-matrix conjugate, and then the labeled biomolecule essentially free of unbound labeling reagent is removed. Also included is a novel chelator IDAC-2, which may be used for labeling biomolecules and for scavenging in the chelator-matrix conjugate.