发明名称 |
DIMERIC ARYLISOQUINOLINE ALKALOIDS AND SYNTHESIS METHODS THEREOF |
摘要 |
The present invention provides a method of preparing dimeric arylisoquinoline alkaloids by coupling two isoquinoline building blocks, each of which may be the same or different, together with a symmetrical or nonsymmetrical biaryl building block to form homodimers or heterodimers, including the antiviral michellamines. The present invention also provides new, medically useful homodimeric and heterodimeric arylisoquinoline compounds and derivatives thereof.
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申请公布号 |
WO9603381(A1) |
申请公布日期 |
1996.02.08 |
申请号 |
WO1995US09070 |
申请日期 |
1995.07.19 |
申请人 |
THE UNITED STATES OF AMERICA, REPRESENTED BY THE S;THE TRUSTEES OF BOSTON COLLEGE |
发明人 |
BRINGMANN, GERHARD;BOYD, MICHAEL, R.;GOTZ, ROLAND;KELLY, T., ROSS |
分类号 |
A61K31/47;A61K31/472;A61P31/12;C07D217/02;C07D217/04;(IPC1-7):C07D217/02 |
主分类号 |
A61K31/47 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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