ANTIPHLOGISTIC, ANALGESIC, ANTIPYRETIC INJECTION PREPARATION

摘要

An antiphlogistic, analgesic, antipyretic parenteral preparation comprising diclofenac, its salt, or both, a surfactant, and cosurfactant, and water, and having a pH of 3-10 is provided. Another antiphlogistic, analgesic, antipyretic parenteral preparation comprising diclofenac, its salt, or both, a surfactant, and cosurfactant, an oily component, and water, and having a pH of 3-10 is provided. The parenteral preparation can be injected without pain, can avoid occurrence of side effects such as shock, due to the rapid diclofenac plasma concentration increase, that after administration of currently marketed diclofenac preparations, and can exhibit sustained therapeutic levels of diclofenac in plasma.