Compounds of the invention have structure (I) for example formula (II). These compounds inhibit thrombin and associated thrombosis.
申请公布号
CA2193844(A1)
申请公布日期
1996.02.08
申请号
CA19952193844
申请日期
1995.07.18
申请人
MERCK & CO., INC.
发明人
LUMMA, WILLIAM C.;FREIDINGER, ROGER M.;BRADY, STEPHEN F.;SANDERSON, PHILIP E.;FENG, DONG-MEI;LYLE, TERRY ALAN;STAUFFER, KENNETH JAMES;TUCKER, THOMAS JOSEPH;VACCA, JOSEPH P.