| 摘要 |
<p>A method of immunoassaying an antibody characteristic of systemic lupus erythematosus (SLE) and a kit therefor. The quantity of an antibody which combines with a negatively charged substance by means of electrostatic affinity can be obtained by reacting a body fluid with the substance in each of at least three buffers having different ionic strengths, measuring the quantity of the antibody combined with the substance in each buffer, and determining the difference between the minimum value of the measured quantity of the combined antibody and the maximum value of the measured quantity thereof on the lower ionic-strength side. Thus it is possible to assay specifically and easily the autoantibody that combines with an antigen by means of electrostatic affinity and that is thought to relate seriously to the pathological condition of SLE, and to diagnose SLE more accurately.</p> |
