发明名称 Device for analyzing the metabolism of cells
摘要 A device for analyzing the metabolism of cells includes a supporting base which carries a pH measuring electrode, a control electrode designed for proton exchange with the liquid, a reference electrode, and a counterelectrode, and which, together with at least one other part, confines a hollow space containing the cells and a liquid. The electrodes are connected to electronic circuit elements. In the course of an analysis the pH value of the liquid is determined by means of the pH measuring electrode and the reference electrode. Between the control electrode and the counterelectrode an electric current is passed through the liquid and controlled such that the pH of the liquid is maintained at a constant preset value beneficial to the cells, by proton exchange with the control electrode. In addition, the amount of charge required for generating the current during the measuring period is determined to obtain a measure for the intensity of the metabolic process and thus for the vitality of the cells.
申请公布号 US5489515(A) 申请公布日期 1996.02.06
申请号 US19940353268 申请日期 1994.12.05
申请人 AVL MEDICAL INSTRUMENTS AG 发明人 HATSCHEK, RUDOLF;HEITZ, ERICH W. F.
分类号 G01N33/483;C12Q1/02;G01N27/403;G01N27/416;G01N33/84;(IPC1-7):C12Q1/02;G01N27/00 主分类号 G01N33/483
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